Patrick Wunderlich

Sequential Proteolytic Processing of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Protein by Ectodomain Shedding and γ-Secretase-dependent Intramembranous Cleavage

Patrick Wunderlich, Konstantin Glebov, Nadja Kemmerling et al. · Journal of Biological Chemistry · 2013 · 303 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Statins Promote the Degradation of Extracellular Amyloid β-Peptide by Microglia via Stimulation of Exosome-associated Insulin-degrading Enzyme (IDE) Secretion

Irfan Y. Tamboli, Esther Barth, Leonie Christian et al. · Journal of Biological Chemistry · 2010 · 215 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Aging‐related increase in oxidative stress correlates with developmental pattern of beta‐secretase activity and beta‐amyloid plaque formation in transgenic Tg2576 mice with Alzheimer‐like pathology

Jenny Apelt, Marina Bigl, Patrick Wunderlich et al. · International Journal of Developmental Neuroscience · 2004 · 173 citations

Life Sciences, Neurobiology, Neuroscience +17

Presenilin-1 L166P Mutant Human Pluripotent Stem Cell–Derived Neurons Exhibit Partial Loss of γ-Secretase Activity in Endogenous Amyloid-β Generation

Philipp Koch, Irfan Y. Tamboli, Jérôme Mertens et al. · American Journal Of Pathology · 2012 · 113 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity

Sathish Kumar, Oliver Wirths, Kathrin Stüber et al. · Acta Neuropathologica · 2016 · 106 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17