Alexander Karollus

Current sequence-based models capture gene expression determinants in promoters but mostly ignore distal enhancers

Alexander Karollus, Thomas Mauermeier, Julien Gagneur · Genome biology · 2023 · 115 citations · Full text

AlphaGenome: advancing regulatory variant effect prediction with a unified DNA sequence model

Žiga Avsec, Natasha S. Latysheva, Jun Cheng et al. · 2025 · 79 citations · Full text

Engineering, Neurogenomics, Genetics +22

Predicting mean ribosome load for 5’UTR of any length using deep learning

Alexander Karollus, Žiga Avsec, Julien Gagneur · PLoS Computational Biology · 2021 · 52 citations · Full text

Engineering, Genetics, Mrna Translation +19

Species-aware DNA language models capture regulatory elements and their evolution

Alexander Karollus, Johannes Hingerl, Dennis Gankin et al. · Genome biology · 2024 · 42 citations · Full text

The adapted Activity-By-Contact model for enhancer–gene assignment and its application to single-cell data

Dennis Hecker, Fatemeh Behjati Ardakani, Alexander Karollus et al. · Bioinformatics · 2023 · 28 citations · Full text