Joanne Lerpiniere

The HgCl2-promoted guanylation reaction: The scope and limitations

Catherine Levallet, Joanne Lerpiniere, Soo Y. Ko · Tetrahedron · 1997 · 118 citations

Reaction Intermediate, Hgcl2-promoted Guanylation Reaction, Biomolecular Engineering +1

Antagonists of the Human A_2A Adenosine Receptor. 4. Design, Synthesis, and Preclinical Evaluation of 7-Aryltriazolo[4,5-<i>d</i>]pyrimidines

Roger J. Gillespie, Samantha J. Bamford, Ruth Botting et al. · Journal of Medicinal Chemistry · 2008 · 103 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Striatal Dopamine +14

Discovery of nonxanthine adenosine A_2Areceptor antagonists for the treatment of Parkinson’s disease

Scott Μ. Weiss, Karen Benwell, Ian A. Cliffe et al. · Neurology · 2003 · 77 citations

Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpurines

Roger J. Gillespie, Ian A. Cliffe, Claire Dawson et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 65 citations · Full text

Biochemistry, Medicine, Mechanism Of Action +5

2-Nitrophenylcarbamoyl-(<i>S</i>)-prolyl-(<i>S</i>)-3-(2-naphthyl)alanyl-<i>N</i>-benzyl-<i>N</i>- methylamide (SDZ NKT 343), a Potent Human NK₁ Tachykinin Receptor Antagonist with Good Oral Analgesic Activity in Chronic Pain Models

Christopher Walpole, Sun Young Ko, Michael C. Brown et al. · Journal of Medicinal Chemistry · 1998 · 65 citations · Full text

Pain Disorders, Pain Medicine, Benzylthiourea Substituent +23