Brian Lockhart

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

András Kotschy, Zoltán Szlávik, James B. Murray et al. · Nature · 2016 · 1K citations

Mcl1 Inhibitor S63845, Systems Biology, Oncology +11

Amnesia induced in mice by centrally administered β-amyloid peptides involves cholinergic dysfunction

Tangui Maurice, Brian Lockhart, Alain Privat · Brain Research · 1996 · 516 citations

Synaptic Plasticity, Neurodegenerative Diseases, Synaptic Signaling +13

A convenient extension of the Wessely–Moser rearrangement for the synthesis of substituted alkylaminoflavones as neuroprotective agents in vitro

Ronan Larget, Brian Lockhart, Pierre Renard et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 118 citations · Full text

Wessely–moser Rearrangement, Bioorganic Chemistry, Substituted Alkylaminoflavones +5

Genetic Deletion of Trace Amine 1 Receptors Reveals Their Role in Auto-Inhibiting the Actions of Ecstasy (MDMA)

Benjamin Di Cara, Roberto Maggio, Gabriella Aloisi et al. · Journal of Neuroscience · 2011 · 97 citations · Full text

Only a Subset of Met-Activated Pathways Are Required to Sustain Oncogene Addiction

Andrea Bertotti, Mike F. Burbridge, Stefania Gastaldi et al. · Science Signaling · 2009 · 93 citations · Full text

Tumor Onset, Cancer Biology, Tumor Biology +18