Patrick A. Ozark

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy

Lu Wang, Zibo Zhao, Patrick A. Ozark et al. · Nature Medicine · 2018 · 191 citations · Full text

Cancer Therapy, Chromatin, Chromatin Remodeling +10

TET2 coactivates gene expression through demethylation of enhancers

Lu Wang, Patrick A. Ozark, Edwin R. Smith et al. · Science Advances · 2018 · 153 citations · Full text

Epigenetic Change, Genetics, Dna Methylation +18

PAF1 regulation of promoter-proximal pause release via enhancer activation

Fei Chen, Peng Xie, Clayton K. Collings et al. · Science · 2017 · 144 citations · Full text

Transcriptional Regulation, Systems Biology, Paf1 Target Genes +12

Histone H3K4 methylation-dependent and -independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation

Christie C. Sze, Kaixiang Cao, Clayton K. Collings et al. · Genes & Development · 2017 · 124 citations · Full text

Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy

Kaiwei Liang, Edwin R. Smith, Yuki Aoi et al. · Cell · 2018 · 124 citations · Full text

Tumor Biology, Transcriptional Regulation, Sec Disruption +9