Edwin R. Smith

Physical Association and Coordinate Function of the H3 K4 Methyltransferase MLL1 and the H4 K16 Acetyltransferase MOF

Yali Dou, Thomas A. Milne, Alan J. Tackett et al. · Cell · 2005 · 670 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

Chengqi Lin, Edwin R. Smith, Hidehisa Takahashi et al. · Molecular Cell · 2010 · 575 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +9

The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers

Deqing Hu, Xin Gao, Marc A. Morgan et al. · Molecular and Cellular Biology · 2013 · 433 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II

Pengfei Wang, Chengqi Lin, Edwin R. Smith et al. · Molecular and Cellular Biology · 2009 · 362 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

A Human Protein Complex Homologous to the <i>Drosophila</i> MSL Complex Is Responsible for the Majority of Histone H4 Acetylation at Lysine 16

Edwin R. Smith, Christelle Cayrou, Rong Huang et al. · Molecular and Cellular Biology · 2005 · 335 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15