Violetta Steeples

U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies

Molly A. Smith, Gaurav S. Choudhary, Andrea Pellagatti et al. · Nature Cell Biology · 2019 · 252 citations

Medicine, Molecular Genetics, Oncology +11

Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations

Andrea Pellagatti, Richard N. Armstrong, Violetta Steeples et al. · Blood · 2018 · 250 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

A Mutation in the Mitochondrial Fission Gene Dnm1l Leads to Cardiomyopathy

Houman Ashrafian, Louise Docherty, Vincenzo Leo et al. · PLoS Genetics · 2010 · 144 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Cryptic splicing events in the iron transporter ABCB7 and other key target genes in SF3B1-mutant myelodysplastic syndromes

Hamid Dolatshad, Andrea Pellagatti, Fabio G. Liberante et al. · Leukemia · 2016 · 136 citations · Full text

Life Sciences, Genetics, Hematology +17

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

Arash Yavari, Claire J. Stocker, Sahar Ghaffari et al. · Cell Metabolism · 2016 · 111 citations · Full text

Life Sciences, Biochemistry, Physiology +17