Lee S. Chong

Utilization of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold in the design of potent inhibitors of serine proteases: SAR studies using carboxylates

Rongze Kuang, Jeffrey B. Epp, Sumei Ruan et al. · Bioorganic & Medicinal Chemistry · 2000 · 51 citations

Combinatorial Chemistry, Medicinal Chemistry, 1,2,5-Thiadiazolidin-3-one 1,1 +11

Asymmetric Synthesis of Calyculin C. 1. Synthesis of the C₁−C₂₅ Fragment

Gerard R. Scarlato, John A. DeMattei, Lee S. Chong et al. · The Journal of Organic Chemistry · 1996 · 42 citations

Combinatorial Chemistry, Medicinal Chemistry, Serine/threonine Phosphatase Pp1 +15

Isoxazoline derivatives as potential inhibitors of the proteolytic enzymes human leukocyte elastase, cathepsin G and proteinase 3: a structure-activity relationship study

William C. Groutas, R. Venkataraman, Lee S. Chong et al. · Bioorganic & Medicinal Chemistry · 1995 · 39 citations

Cellular Enzymology, Biochemistry, Cathepsin G +13

Discovery of GS-9669, a Thumb Site II Non-Nucleoside Inhibitor of NS5B for the Treatment of Genotype 1 Chronic Hepatitis C Infection

Scott E. Lazerwith, Willard Lew, Jennifer Zhang et al. · Journal of Medicinal Chemistry · 2013 · 36 citations

Drug Target, Antiviral Drug, Chemical Biology +17

HCV NS5B polymerase inhibitors.

William J. Watkins, Adrian S. Ray, Lee S. Chong · PubMed · 2010 · 33 citations

Medicinal Chemistry, Hcv Ns5b Polymerase, Viral Polymerase Structure +15