Rongze Kuang

Structure-Based Design of a General Class of Mechanism-Based Inhibitors of the Serine Proteinases Employing a Novel Amino Acid-Derived Heterocyclic Scaffold

William C. Groutas, Rongze Kuang, R. Venkataraman et al. · Biochemistry · 1997 · 79 citations

Discovery of a Novel Class of Orally Active Antifungal β-1,3- <scp>d</scp> -Glucan Synthase Inhibitors

Scott S. Walker, Yiming Xu, Ilias Triantafyllou et al. · Antimicrobial Agents and Chemotherapy · 2011 · 75 citations · Full text

Medicinal Chemistry, Antifungal Agent, Biochemistry +11

Potent and Specific Inhibition of Human Leukocyte Elastase, Cathepsin G and Proteinase 3 by Sulfone Derivatives Employing the 1,2,5-Thiadiazolidin-3-one 1,1 Dioxide Scaffold

William C. Groutas, Rongze Kuang, Sumei Ruan et al. · Bioorganic & Medicinal Chemistry · 1998 · 71 citations

Specific Inhibition, Medicinal Chemistry, Cellular Enzymology +11

A General Inhibitor Scaffold for Serine Proteases with a (Chymo)trypsin-Like Fold:  Solution-Phase Construction and Evaluation of the First Series of Libraries of Mechanism-Based Inhibitors

Rongze Kuang, Jeffrey B. Epp, Sumei Ruan et al. · Journal of the American Chemical Society · 1999 · 55 citations

Protein Assembly, General Inhibitor Scaffold, Altmetric Attention Score +22

Utilization of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold in the design of potent inhibitors of serine proteases: SAR studies using carboxylates

Rongze Kuang, Jeffrey B. Epp, Sumei Ruan et al. · Bioorganic & Medicinal Chemistry · 2000 · 51 citations

Combinatorial Chemistry, Medicinal Chemistry, 1,2,5-Thiadiazolidin-3-one 1,1 +11