Leslie R. Walker

A Class of 2,4-Bisanilinopyrimidine Aurora A Inhibitors with Unusually High Selectivity against Aurora B

Ignacio Aliagas-Martin, Dan Burdick, Laura Corson et al. · Journal of Medicinal Chemistry · 2009 · 81 citations · Full text

Molecular Biology, Organic Chemistry, Pharmacotherapy +16

Cell penetrating peptides fused to a thermally targeted biopolymer drug carrier improve the delivery and antitumor efficacy of an acid-sensitive doxorubicin derivative

Leslie R. Walker, Eddie Perkins, Felix Kratz et al. · International Journal of Pharmaceutics · 2012 · 71 citations · Full text

Cell-based Drug Delivery, Nanomedicine, Engineering +7

A Pentacyclic Aurora Kinase Inhibitor (AKI-001) with High in Vivo Potency and Oral Bioavailability

Thomas E. Rawson, Matthias Rüth, Elizabeth Blackwood et al. · Journal of Medicinal Chemistry · 2008 · 58 citations · Full text

Medicinal Chemistry, Oral Bioavailability, Novel Therapy +14

Synthesis and investigation of novel spiro-isoxazolines as anti-cancer agents

Prasanta Das, Ann O. Omollo, Lungile Sitole et al. · Tetrahedron Letters · 2015 · 37 citations · Full text

Novel Spiro-isoxazolines, Medicinal Chemistry, Medicine +4

Fusion of cell-penetrating peptides to thermally responsive biopolymer improves tumor accumulation of p21 peptide in a mouse model of pancreatic cancer

Leslie R. Walker, Jung Su Ryu, Eddie Perkins et al. · Drug Design Development and Therapy · 2014 · 21 citations · Full text

Engineering, P21 Peptide, Peptide Engineering +20