Marlen Metzner

Senescence-associated reprogramming promotes cancer stemness

Maja Milanovic, Dorothy Ngo-Yin Fan, Dimitri Belenki et al. · Nature · 2017 · 1.1K citations

Tumor Biology, Lineage Plasticity, Stem Cell Research +4

Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib

Lynn Quek, Muriel D. David, Alison Kennedy et al. · Nature Medicine · 2018 · 193 citations · Full text

Hematological Malignancy, Clonal Heterogeneity, Medicine +11

Genetically distinct leukemic stem cells in human CD34− acute myeloid leukemia are arrested at a hemopoietic precursor-like stage

Lynn Quek, Georg Otto, Catherine Garnett et al. · The Journal of Experimental Medicine · 2016 · 146 citations · Full text

Cell Surface Cd34, Mixed-phenotype Acute Leukemia, Lsc Differentiation Arrest +18

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome

Maurice Labuhn, Kelly Perkins, Sören Matzk et al. · Cancer Cell · 2019 · 140 citations · Full text

Down Syndrome, Myeloid Preleukemia, Transformed Myeloid Leukemia +8

Outcome of Azacitidine Therapy in Acute Myeloid Leukemia Is not Improved by Concurrent Vorinostat Therapy but Is Predicted by a Diagnostic Molecular Signature

Charles Craddock, Aimee E. Houlton, Lynn Quek et al. · Clinical Cancer Research · 2017 · 85 citations · Full text