Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acid

Deepak Menon, Darin Salloum, Elyssa Bernfeld, +7

Journal of Biological Chemistry

Lipid SensingBiochemistryPhosphatidic AcidLipid MovementLipid Chemistry +2

Angiopoietin-like 4 binds neuropilins and cooperates with VEGF to induce diabetic macular edema

Akrit Sodhi, Tao Ma, Deepak Menon, +6

Journal of Clinical Investigation

Ocular DiseaseAngiopoietin-like 4Retinal Vascular LeakageDiabetic Macular EdemaRetinal Therapies +15

Aspartate Rescues S-phase Arrest Caused by Suppression of Glutamine Utilization in KRas-driven Cancer Cells

Deven Patel, Deepak Menon, Elyssa Bernfeld, +4

Journal of Biological Chemistry

Amino Acids and mTOR Mediate Distinct Metabolic Checkpoints in Mammalian G1 Cell Cycle

Mahesh Saqcena, Deepak Menon, Deven Patel, +3

PLoS ONE

Phospholipase D–dependent mTOR complex 1 (mTORC1) activation by glutamine

Elyssa Bernfeld, Deepak Menon, Vishaldeep Vaghela, +4

Journal of Biological Chemistry

Phosphatidic acid drives mTORC1 lysosomal translocation in the absence of amino acids

María A. Frías, Suman Mukhopadhyay, Elyssa Lehman, +4

Journal of Biological Chemistry

Novel low-shrinkage-stress nanocomposite with remineralization and antibacterial abilities to protect marginal enamel under biofilm

Ghalia Bhadila, Xiaohong Wang, Wen Zhou, +7

Journal of Dentistry

Materials ScienceMarginal EnamelEngineeringNanomaterialsOperative Dentistry +3

Apoptotic effects of high-dose rapamycin occur in S-phase of the cell cycle

Mahesh Saqcena, Deven Patel, Deepak Menon, +2

Cell Cycle

Tumor BiologyCell RegulationCell DivisionMedicineCell Death +13

ANGPTL4 influences the therapeutic response of patients with neovascular age-related macular degeneration by promoting choroidal neovascularization

Qin Yu, Aumreetam Dinabandhu, Xuan Cao, +15

JCI Insight

Ocular DiseaseImmunologyTherapeutic ResponseChoroidal NeovascularizationRetinal Therapies +17

Long-term antibacterial activity and cytocompatibility of novel low-shrinkage-stress, remineralizing composites

Ghalia Bhadila, Deepak Menon, Xiaohong Wang, +8

Journal of Biomaterials Science Polymer Edition