Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry

Xiaodong Feng, María Sol Degese, Ramiro Iglesias‐Bartolomé, +9

Cancer Cell

Systems BiologySignal TransductionSignaling PathwayG Protein-coupled ReceptorHippo-independent Activation +6

The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha.

Akrit Sodhi, Silvia Montaner, V. Patel, +4

PubMed

ImmunologyTumor BiologyViral OncologyCancer-associated VirusInflammation +17

Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes

Silvia Montaner, Akrit Sodhi, Alfredo A. Molinolo, +6

Cancer Cell

Viral Latent GenesMolecular VirologyViral PathogenesisPathologyVirology +7

Mammalian Target of Rapamycin, a Molecular Target in Squamous Cell Carcinomas of the Head and Neck

Panomwat Amornphimoltham, Vyomesh Patel, Akrit Sodhi, +5

Cancer Research

The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B.

Silvia Montaner, Akrit Sodhi, Salvatore Pece, +2

PubMed

Viral PathogenesisImmunologyPathologyCell DeathTumor Biology +15

The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor

Akrit Sodhi, Risa Chaisuparat, Jiadi Hu, +7

Cancer Cell

Signal TransductionSignaling PathwayReceptor Tyrosine KinaseImmunologyEndothelial Cell Transformation +8

Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche

Zhiping Liu, Jiean Xu, Qian Ma, +15

Science Translational Medicine

Rac1 Function Is Required for Src-induced Transformation

Joan‐Marc Servitja, María Julia Marinissen, Akrit Sodhi, +2

Journal of Biological Chemistry

Signal TransductionRac1 FunctionCell RegulationMolecular RegulationTyrosine Residues +12

Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy

Jiong Hu, Sarah Dziumbla, Jihong Lin, +19

Nature

Diabetic RetinopathyOcular DiseaseOphthalmologyMedicineDiabetes +2

MAPK and Akt Act Cooperatively but Independently on Hypoxia Inducible Factor-1α in rasV12 Upregulation of VEGF

Akrit Sodhi, Silvia Montaner, Hiroshi Miyazaki, +1

Biochemical and Biophysical Research Communications

Transcriptional RegulationRasv12 UpregulationSignal TransductionMolecular PhysiologySignaling Pathway +10