Uwe Trinks

Modelling study of protein kinase inhibitors: Binding mode of staurosporine and origin of the selectivity of CGP 52411

Pascal Furet, Giorgio Caravatti, Nicholas Lydon et al. · Journal of Computer-Aided Molecular Design · 1995 · 103 citations

Molecular Docking, Drug Target, Signal Transduction +12

4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity.

Elisabeth Buchdunger, Uwe Trinks, Helmut Mett et al. · Proceedings of the National Academy of Sciences · 1994 · 99 citations · Full text

Cancer Research, Signal Transduction, Signaling Pathway +13

Dianilinophthalimides: Potent and Selective, ATP-Competitive Inhibitors of the EGF-Receptor Protein Tyrosine Kinase

Uwe Trinks, Elisabeth Buchdunger, Pascal Furet et al. · Journal of Medicinal Chemistry · 1994 · 90 citations · Full text

Medicinal Chemistry, Signal Transduction, Biochemistry +15

[(Alkylamino)methyl]acrylophenones: Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase

Peter Traxler, Uwe Trinks, Elisabeth Buchdunger et al. · Journal of Medicinal Chemistry · 1995 · 77 citations · Full text

Nude Mouse Model, Medicinal Chemistry, Medicine +14

Ethylene Biosynthesis part 10. Synthesis and study of racemic, (1<i>R</i>, 2<i>S</i>)‐, and (1<i>S</i>, 2<i>R</i>)‐1‐Amino‐2‐(hydroxymethyl)cyclopropanecarboxylic Acid

Michael C. Pirrung, S.E. Dunlap, Uwe Trinks · Helvetica Chimica Acta · 1989 · 73 citations

Cyclopropanecarboxylic Acid, Biosynthesis, Bioorganic Chemistry +15