Vidya P. Ramamurthy

Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts<i>in vivo</i>

Andrew K. Kwegyir‐Afful, Senthilmurugan Ramalingam, Puranik Purushottamachar et al. · Oncotarget · 2015 · 99 citations · Full text

First Mnks degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer cell lines

Senthilmurugan Ramalingam, Lalji K. Gediya, Andrew K. Kwegyir‐Afful et al. · Oncotarget · 2014 · 55 citations · Full text

The retinamide <scp>VNLG</scp>‐152 inhibits <scp>f‐AR</scp>/<scp>AR</scp>‐V7 and <scp>MNK</scp>–<scp>eIF</scp>4E signaling pathways to suppress <scp>EMT</scp> and castration‐resistant prostate cancer xenograft growth

Vidya P. Ramamurthy, Senthilmurugan Ramalingam, Lalji K. Gediya et al. · FEBS Journal · 2018 · 34 citations · Full text

Novel C-4 Heteroaryl 13-<i>cis</i>-Retinamide Mnk/AR Degrading Agents Inhibit Cell Proliferation and Migration and Induce Apoptosis in Human Breast and Prostate Cancer Cells and Suppress Growth of MDA-MB-231 Human Breast and CWR22Rv1 Human Prostate Tumor Xenografts in Mice

Hannah W. Mbatia, Senthilmurugan Ramalingam, Vidya P. Ramamurthy et al. · Journal of Medicinal Chemistry · 2015 · 31 citations · Full text

Lead Compounds, Chemoprevention Strategy, Cell Death +18

Galeterone and The Next Generation Galeterone Analogs, VNPP414 and VNPP433-3β Exert Potent Therapeutic Effects in Castration-/Drug-Resistant Prostate Cancer Preclinical Models In Vitro and In Vivo

Andrew K. Kwegyir‐Afful, Senthilmurugan Ramalingam, Vidya P. Ramamurthy et al. · Cancers · 2019 · 30 citations · Full text