David Sperandio

Synthesis of 3,5-disubstituted-1,2,4-oxadiazoles using tetrabutylammonium fluoride as a mild and efficient catalyst

Anthony R. Gangloff, Joane Litvak, Emma Shelton et al. · Tetrahedron Letters · 2001 · 120 citations

Chemical Engineering, Engineering, Natural Sciences +9

Discovery of an Oral Respiratory Syncytial Virus (RSV) Fusion Inhibitor (GS-5806) and Clinical Proof of Concept in a Human RSV Challenge Study

Richard L. Mackman, Michael Sangi, David Sperandio et al. · Journal of Medicinal Chemistry · 2015 · 120 citations

Immunology, Pharmacology, Rsv Infection +12

A New and Selective Catalyst for the [5 + 2] Cycloaddition of Vinylcyclopropanes and Alkynes

Paul A. Wender, David Sperandio · The Journal of Organic Chemistry · 1998 · 117 citations

Chemical Engineering, Engineering, Heterocyclic +9

The Structure of the Extracellular Region of Human Hepsin Reveals a Serine Protease Domain and a Novel Scavenger Receptor Cysteine-Rich (SRCR) Domain

John R. Somoza, Joseph D. Ho, Christine Luong et al. · Structure · 2003 · 85 citations · Full text

Extracellular Region, Protein Function, Signal Transduction +10

Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle

Richard L. Mackman, Victoria A. Steadman, David K. Dean et al. · Journal of Medicinal Chemistry · 2018 · 75 citations · Full text