Ethnobotanical-Directed Discovery of the Antihyperglycemic Properties of Cryptolepine: Its Isolation from <i>Cryptolepis</i> <i>sanguinolenta</i>, Synthesis, and in Vitro and in Vivo Activities

Donald Bierer, Diana M. Fort, Christopher D. Mendez, +15

Journal of Medicinal Chemistry

Synthesis of 3,5-disubstituted-1,2,4-oxadiazoles using tetrabutylammonium fluoride as a mild and efficient catalyst

Anthony R. Gangloff, Joane Litvak, Emma Shelton, +3

Tetrahedron Letters

Chemical EngineeringEngineeringNatural SciencesTetrabutylammonium FluorideDiversity-oriented Synthesis +7

Antihyperglycemic Activities of Cryptolepine Analogues:  An Ethnobotanical Lead Structure Isolated from<i>Cryptolepis sanguinolenta</i>

Donald Bierer, L. G. DUBENKO, Pingsheng Zhang, +11

Journal of Medicinal Chemistry

A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site11Edited by D. Rees

B.A. Katz, Kyle Elrod, Christine Luong, +12

Journal of Molecular Biology

Protein AssemblyBiochemistryProtein FoldingD. ReesNatural Sciences +7

Novel 1,2-Dithiins: Synthesis, Molecular Modeling Studies, and Antifungal Activity

Donald Bierer, Jeffrey M. Dener, L. G. DUBENKO, +5

Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryAntifungal AgentHeterocyclicBiochemistry +13

Highly potent non-peptidic inhibitors of the HCV NS3/NS4A serine protease

David Sperandio, Anthony R. Gangloff, Joane Litvak, +14

Bioorganic & Medicinal Chemistry Letters

Protease InhibitorsBiochemistryMedicineAntiviral Drug DevelopmentAntiviral Therapy +5

Synthetic Analogues of Irlbacholine:  A Novel Antifungal Plant Metabolite Isolated from <i>Irlbachia </i><i>Alata</i>

Qing Lü, Rosa Ubillas, Yihong Zhou, +9

Journal of Natural Products

Medicinal ChemistryAntifungal AgentBioorganic ChemistryBiochemistryAntifungal Agents +12

Discovery of 5-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-7-phenyl-(E)-2,3,6,7-tetrahydro-1,4-thiazepines as a new series of apoptosis inducers using a cell- and caspase-based HTS assay

John Drewe, Shailaja Kasibhatla, Ben Tseng, +7

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryMedicineNatural SciencesApoptosis +10

Total Synthesis of Cacalol

Albert W. Garofalo, Joane Litvak, Lisa Wang, +3

The Journal of Organic Chemistry

Medicinal ChemistryPharmaceutical ScienceNatural SciencesMedicineChemical Derivative +12

Discovery and structure–activity relationship of 2-phenyl-oxazole-4-carboxamide derivatives as potent apoptosis inducers

Vincent W.‐F. Tai, David Sperandio, Emma Shelton, +27

Bioorganic & Medicinal Chemistry Letters

Structure–activity RelationshipMedicinal ChemistryBiochemistryMedicineNatural Sciences +9