Stephen C. Yabut

Potent, Small-Molecule Inhibitors of Human Mast Cell Tryptase. Antiasthmatic Action of a Dipeptide-Based Transition-State Analogue Containing a Benzothiazole Ketone

Michael J. Costanzo, Stephen C. Yabut, Harold R. Almond et al. · Journal of Medicinal Chemistry · 2003 · 81 citations · Full text

Mast Cell Disorder, Antiasthmatic Action, Benzothiazole Ketone +21

Potent, Orally Active GPIIb/IIIa Antagonists Containing a Nipecotic Acid Subunit. Structure−Activity Studies Leading to the Discovery of RWJ-53308

William J. Hoekstra, Bruce E. Maryanoff, Bruce P. Damiano et al. · Journal of Medicinal Chemistry · 1999 · 71 citations · Full text

Active Gpiib/iiia Antagonists, Pharmacotherapy, Chemical Biology +20

Potent Thrombin Inhibitors That Probe the S₁‘ Subsite:  Tripeptide Transition State Analogues Based on a Heterocycle-Activated Carbonyl Group

Michael J. Costanzo, Bruce E. Maryanoff, Leonard R. Hecker et al. · Journal of Medicinal Chemistry · 1996 · 65 citations · Full text

Pharmaceutical Science, Drug Target, Heterocycle-activated Carbonyl Group +22

In-Depth Study of Tripeptide-Based α-Ketoheterocycles as Inhibitors of Thrombin. Effective Utilization of the S₁‘ Subsite and Its Implications to Structure-Based Drug Design

Michael J. Costanzo, Harold R. Almond, Leonard R. Hecker et al. · Journal of Medicinal Chemistry · 2004 · 65 citations · Full text

Pharmaceutical Science, Thrombin Inhibitors, In-depth Study +19

Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives

Michael J. Costanzo, Stephen C. Yabut, Han-Cheng Zhang et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 53 citations · Full text

Medicinal Chemistry, Allergy, Medicine +9