Leonard R. Hecker

Improved Procedures for the Preparation of Cycloalkyl-, Arylalkyl-, and Arylthioureas

C. R. Rasmussen, Frank J. Villani, Larry E. Weaner et al. · Synthesis · 1988 · 94 citations

Natural Sciences, Chemistry, Organic Chemistry +3

Potent, Orally Active GPIIb/IIIa Antagonists Containing a Nipecotic Acid Subunit. Structure−Activity Studies Leading to the Discovery of RWJ-53308

William J. Hoekstra, Bruce E. Maryanoff, Bruce P. Damiano et al. · Journal of Medicinal Chemistry · 1999 · 71 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

In-Depth Study of Tripeptide-Based α-Ketoheterocycles as Inhibitors of Thrombin. Effective Utilization of the S₁‘ Subsite and Its Implications to Structure-Based Drug Design

Michael J. Costanzo, Harold R. Almond, Leonard R. Hecker et al. · Journal of Medicinal Chemistry · 2004 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3

Han‐Cheng Zhang, Hong Ye, Claudia K. Derian et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 66 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +10

Potent Thrombin Inhibitors That Probe the S₁‘ Subsite:  Tripeptide Transition State Analogues Based on a Heterocycle-Activated Carbonyl Group

Michael J. Costanzo, Bruce E. Maryanoff, Leonard R. Hecker et al. · Journal of Medicinal Chemistry · 1996 · 65 citations · Full text

Pharmacy, Chemistry, Pharmacology +10