Wilbert Zwart

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Glued and late endosome positioning

Nuno Rocha, Coenraad Kuijl, Rik van der Kant et al. · The Journal of Cell Biology · 2009 · 675 citations · Full text

Activation of endosomal dynein motors by stepwise assembly of Rab7–RILP–p150Glued, ORP1L, and the receptor βlll spectrin

Marie Johansson, Nuno Rocha, Wilbert Zwart et al. · The Journal of Cell Biology · 2007 · 484 citations · Full text

Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis

Max D. Wellenstein, Seth B. Coffelt, Danique E. M. Duits et al. · Nature · 2019 · 484 citations

Inflammation, Breast Cancer Metastasis, Breast Oncology +8

Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin

Baoxu Pang, Xiaohang Qiao, Lennert Janssen et al. · Nature Communications · 2013 · 423 citations · Full text

Histone Modifications, Molecular Biology, Drug-induced Histone Eviction +17

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9

Gözde Korkmaz, Rui Lopes, Alejandro P. Ugalde et al. · Nature Biotechnology · 2016 · 419 citations

Enhancer Elements, Engineering, Cell Modification +12