John P. Wolak

Three Mechanistically Distinct Kinase Assays Compared: Measurement of Intrinsic ATPase Activity Identified the Most Comprehensive Set of ITK Inhibitors

Mohammed A. Kashem, Richard M. Nelson, Jeffrey D. Yingling et al. · SLAS DISCOVERY · 2006 · 132 citations · Full text

Discovery of potent and selective PKC-θ inhibitors

Charles L. Cywin, Georg Dahmann, Anthony S. Prokopowicz et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 69 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Drug Target +7

Hit to Lead Account of the Discovery of a New Class of Inhibitors of Pim Kinases and Crystallographic Studies Revealing an Unusual Kinase Binding Mode

Kevin Qian, Lian Wang, Charles L. Cywin et al. · Journal of Medicinal Chemistry · 2009 · 69 citations · Full text

Pim Kinases, Pim-2 Sar, Molecular Biology +18

Hit-to-lead studies on benzimidazole inhibitors of ITK: Discovery of a novel class of kinase inhibitors

Roger J. Snow, Asitha Abeywardane, Scot Campbell et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 65 citations · Full text

Benzimidazole Inhibitors, Medicinal Chemistry, Drug Target +13

Optimization of 2-Phenylaminoimidazo[4,5-<i>h</i>]isoquinolin-9-ones:  Orally Active Inhibitors of lck Kinase

Daniel R. Goldberg, Tanja Butz, Mario Cardozo et al. · Journal of Medicinal Chemistry · 2003 · 45 citations · Full text

Pharmaceutical Science, Immunology, Cell Death +16