A Novel Antiinflammatory Maintains Glucocorticoid Efficacy with Reduced Side Effects

Michael J. Coghlan, Peer B. Jacobson, Ben Lane, +12

Molecular Endocrinology

InflammationAnti-inflammatoryG Protein-coupled ReceptorMedicineImmunology +11

A synthesis of protected aminoalkyl epoxides from .alpha.-amino acids

Jay R. Luly, Joseph F. Dellaria, Jacob J. Plattner, +2

The Journal of Organic Chemistry

.Alpha.-amino AcidsBioorganic ChemistryBiochemistryDonut IconNatural Sciences +8

Routes to mitomycins. Chirospecific synthesis of aziridinomitosenes

Kenneth J. Shaw, Jay R. Luly, Henry Rapoport

The Journal of Organic Chemistry

Pharmaceutical ScienceBioorganic ChemistryEngineeringAltmetric Attention ScoreOrganic Chemistry +14

3,5-Bis(trifluoromethyl)pyrazoles:  A Novel Class of NFAT Transcription Factor Regulator

Stevan W. Djurić, Nwe Y. BaMaung, Anwer Basha, +26

Journal of Medicinal Chemistry

Molecular RegulationImmunologyPharmacotherapyChemical BiologyPharmaceutical Chemistry +16

Isotope-Edited NMR of Cyclosporin a Bound to Cyclophilin: Evidence for a <i>Trans</i> 9,10 Amide Bond

Stephen W. Fesik, Robert T. Gampe, Thomas F. Holzman, +7

Science

New inhibitors of human renin that contain novel Leu-Val replacements

Jay R. Luly, Nwe Yi, Jeff Soderquist, +4

Journal of Medicinal Chemistry

Potent Inhibition of NFAT Activation and T Cell Cytokine Production by Novel Low Molecular Weight Pyrazole Compounds

James M. Trevillyan, X. Grace Chiou, Yung‐Wu Chen, +13

Journal of Biological Chemistry

Neointimal Formation After Balloon-Induced Vascular Injury in Yucatan Minipigs is Reduced by Oral Rapamycin

Sandra E. Burke, Nathan L. Lubbers, Yung‐Wu Chen, +4

Journal of Cardiovascular Pharmacology

Synthesis and Characterization of Non-Steroidal Ligands for the Glucocorticoid Receptor:  Selective Quinoline Derivatives with Prednisolone-Equivalent Functional Activity

Michael J. Coghlan, Philip R. Kym, Steven W. Elmore, +10

Journal of Medicinal Chemistry

Medicinal ChemistryAllergyPrednisolone-equivalent Functional ActivityG Protein-coupled ReceptorMedicine +10

Isotope-edited proton NMR study on the structure of a pepsin/inhibitor complex

Stephen W. Fesik, Jay R. Luly, John W. Erickson, +1

Biochemistry

Structural BioinformaticsBiomolecular Structure PredictionPepsin/inhibitor ComplexMolecular BiologyChemical Biology +14