Charmaine Lang

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons

Hugo J. R. Fernandes, Elizabeth M. Hartfield, Helen Christian et al. · Stem Cell Reports · 2016 · 350 citations · Full text

Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes

Charmaine Lang, Kieran R. Campbell, Brent J. Ryan et al. · Cell stem cell · 2018 · 185 citations · Full text

Neurodegenerative Diseases, Identifies Hdac4, Parkinson Cell Phenotypes +9

Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson’s iPSC-derived dopamine neurons

Federico Zambon, Marta Cherubini, Hugo J. R. Fernandes et al. · Human Molecular Genetics · 2019 · 161 citations · Full text

Genetics, Synaptic Signaling, Social Sciences +28

Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson’s disease

Cynthia Sandor, Paul Robertson, Charmaine Lang et al. · Human Molecular Genetics · 2016 · 74 citations · Full text

Transcriptomic Profiling, Neurochemical Biomarkers, Synaptic Signaling +19

<i>α</i>Synuclein and Mitochondrial Dysfunction: A Pathogenic Partnership in Parkinson’s Disease?

David S.W. Protter, Charmaine Lang, Antony A. Cooper · Parkinson s Disease · 2012 · 35 citations · Full text