Toshiko Sakihama

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

Noriko Sakaguchi, Takeshi Takahashi, Hiroshi Hata et al. · Nature · 2003 · 858 citations

Rheumatology, Immunogenetics, Zap-70 Gene Causes +7

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

Makoto Tachibana, Jun Ueda, Mikiko Fukuda et al. · Genes & Development · 2005 · 825 citations · Full text

Histone Modifications, Epigenetic Change, Genetics +18

A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice

Hiroyuki Yoshitomi, Noriko Sakaguchi, Katsuya Kobayashi et al. · The Journal of Experimental Medicine · 2005 · 442 citations · Full text

Skg Arthritis, Immunology, Immune Regulation +17

Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule

Jia‐Huai Wang, Rob Meijers, Yi Xiong et al. · Proceedings of the National Academy of Sciences · 2001 · 263 citations · Full text

Crystal Structure, Medicine, Human Retrovirus +15

Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells

Eiji Nishimura, Toshiko Sakihama, Ruka Setoguchi et al. · International Immunology · 2004 · 233 citations