Toshiko Sakihama

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

Noriko Sakaguchi, Takeshi Takahashi, Hiroshi Hata et al. · Nature · 2003 · 875 citations

Life Sciences, Genetics, Immunology +14

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

Makoto Tachibana, Jun Ueda, Mikiko Fukuda et al. · Genes & Development · 2005 · 830 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice

Hiroyuki Yoshitomi, Noriko Sakaguchi, Katsuya Kobayashi et al. · The Journal of Experimental Medicine · 2005 · 447 citations · Full text

Medicine, Immunology, Pathology +15

Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule

Jia‐Huai Wang, Rob Meijers, Yi Xiong et al. · Proceedings of the National Academy of Sciences · 2001 · 265 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells

Eiji Nishimura, Toshiko Sakihama, Ruka Setoguchi et al. · International Immunology · 2004 · 233 citations

Life Sciences, Cell Biology, Immunology +17