Henry J. Breslin

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

Rudi Pauwels, Koen Andries, Jan Desmyter et al. · Nature · 1990 · 757 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TIBO) derivatives. 2

Michael J. Kukla, Henry J. Breslin, Craig J. Diamond et al. · Journal of Medicinal Chemistry · 1991 · 166 citations

Pharmacy, Chemistry, Medicinal Chemistry +12

Synthesis and Anti-HIV-1 Activity of 4,5,6,7-Tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TIBO) Derivatives. 3

Henry J. Breslin, Michael J. Kukla, Donald Ludovici et al. · Journal of Medicinal Chemistry · 1995 · 97 citations

Pharmacy, Medicinal Chemistry, Pharmacology +6

Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TIBO) derivatives

Michael J. Kukla, Henry J. Breslin, Rudi Pauwels et al. · Journal of Medicinal Chemistry · 1991 · 92 citations

Pharmacy, Medicinal Chemistry, Pharmacology +6

New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs

Rudi Pauwels, Koen Andries, Zeger Debyser et al. · Antimicrobial Agents and Chemotherapy · 1994 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13