Common and Distinct Clinical Features in Adult Patients with Anti-Aminoacyl-tRNA Synthetase Antibodies: Heterogeneity within the Syndrome

Yasuhito Hamaguchi, Manabu Fujimoto, Takashi Matsushita, +12

PLoS ONE

Clinical Correlations With Dermatomyositis-Specific Autoantibodies in Adult Japanese Patients With Dermatomyositis

Yasuhito Hamaguchi, Masataka Kuwana, Kana Hoshino, +29

Archives of Dermatology

Identification of a novel autoantibody reactive with 155 and 140 kDa nuclear proteins in patients with dermatomyositis: an association with malignancy

K. Kaji, Manabu Fujimoto, Minoru Hasegawa, +13

Lara D. Veeken

Antibody isotype-specific engagement of Fcγ receptors regulates B lymphocyte depletion during CD20 immunotherapy

Yasuhito Hamaguchi, Yan Xiu, Kazuhiro Komura, +2

The Journal of Experimental Medicine

CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse

Eriko Saito, Manabu Fujimoto, Minoru Hasegawa, +7

Journal of Clinical Investigation

Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: A novel mouse model for scleroderma?

Jun Wei, Denisa S. Melichian, Kazuhiro Komura, +6

Arthritis & Rheumatism

B-Lymphocyte Depletion Reduces Skin Fibrosis and Autoimmunity in the Tight-Skin Mouse Model for Systemic Sclerosis

Minoru Hasegawa, Yasuhito Hamaguchi, Koichi Yanaba, +10

American Journal Of Pathology

Autoimmune DiseaseCutaneous BiologyImmunologyImmune RegulationSystemic Sclerosis +9

CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse

Eriko Saito, Manabu Fujimoto, Minoru Hasegawa, +7

Journal of Clinical Investigation

Clinical ImmunologySsc PatientsImmune RegulationImmunologyImmunologic Mechanism +26

CD19 Regulates Skin and Lung Fibrosis via Toll-Like Receptor Signaling in a Model of Bleomycin-Induced Scleroderma

Ayumi Yoshizaki, Yohei Iwata, Kazuhiro Komura, +9

American Journal Of Pathology

Inflammatory Lung DiseaseLung InflammationImmunologyImmunologic MechanismInnate Immunity +14

PPARγ Downregulation by TGFß in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis

Jun Wei, Asish K. Ghosh, Jennifer L. Sargent, +7

PLoS ONE