Claudette Mookherjee

The PPARδ agonist GW0742X reduces atherosclerosis in LDLR−/− mice

Tracey L. Graham, Claudette Mookherjee, Keith E. Suckling et al. · Atherosclerosis · 2005 · 200 citations

Life Sciences, Biochemistry, Pharmacology +14

Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators

Simon E. Ward, Mark H Harries, Laura Aldegheri et al. · Journal of Medicinal Chemistry · 2010 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of<i>N</i>-[(2<i>S</i>)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1<i>H</i>-inden-2-yl]-2-propanesulfonamide, a Novel Clinical AMPA Receptor Positive Modulator

Simon E. Ward, Mark H Harries, Laura Aldegheri et al. · Journal of Medicinal Chemistry · 2010 · 47 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

Identification of a sulfonamide series of CCR2 antagonists

Simon Peace, Joanne Philp, Carl Brooks et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 35 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +9

The discovery of a series of N-substituted 3-(4-piperidinyl)-1,3-benzoxazolinones and oxindoles as highly brain penetrant, selective muscarinic M1 agonists

Dale J. Johnson, Ian T. Forbes, Steve P. Watson et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 26 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10