Nina Brinkwirth

Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

James Kramer, Herbert M. Himmel, Anders Lindqvist et al. · Scientific Reports · 2020 · 59 citations · Full text

A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm

Bradley J. Ridder, Derek J. Leishman, Matthew Bridgland‐Taylor et al. · Toxicology and Applied Pharmacology · 2020 · 45 citations · Full text

Ant venoms contain vertebrate-selective pain-causing sodium channel toxins

Samuel D. Robinson, Jennifer R. Deuis, Axel Touchard et al. · Nature Communications · 2023 · 25 citations · Full text

A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model

Xiaomei Han, Mohammadreza Samieegohar, Bradley J. Ridder et al. · Journal of Pharmacological and Toxicological Methods · 2020 · 17 citations · Full text

Reliable identification of cardiac liability in drug discovery using automated patch clamp: Benchmarking best practices and calibration standards for improved proarrhythmic assessment

Nina Brinkwirth, Kiyoshi Takasuna, Masafumi Doi et al. · Journal of Pharmacological and Toxicological Methods · 2020 · 17 citations

Electrophysiological Evaluation, Heart Failure, Patch Clamp +11