Concepedia

James Kramer

JK

10

Publications

1.1K

Citations

10

H-Index

1998

Active since

Affiliations

Charles River Laboratories (United States)(Current)

Center for Drug Evaluation and Research

WesTest Engineering (United States)

University of Oxford

Nanion (Germany)

James Kramer is an author at Charles River Laboratories (United States) specializing in drug discovery, medicine, and pharmacotherapy.

Top concepts

Publications per year

1998–2021

10

Publications

10

MICE Models: Superior to the HERG Model in Predicting Torsade de Pointes

James Kramer, Carlos A. Obejero‐Paz, Glenn J. Myatt et al. · Scientific Reports · 2013 · 345 citations · Full text

Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes

Kimberly R. Doherty, Robert Wappel, Dominique R. Talbert et al. · Toxicology and Applied Pharmacology · 2013 · 166 citations

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Assessment of an <i>In Silico</i> Mechanistic Model for Proarrhythmia Risk Prediction Under the Ci<scp>PA</scp> Initiative

Zhihua Li, Bradley J. Ridder, Xiaomei Han et al. · Clinical Pharmacology & Therapeutics · 2018 · 166 citations · Full text

Modulation of potassium channel gating by coexpression of Kv2.1 with regulatory Kv5.1 or Kv6.1 α-subunits

James Kramer, Marc Post, Arthur Brown et al. · American Journal of Physiology-Cell Physiology · 1998 · 116 citations

Alfuzosin Delays Cardiac Repolarization by a Novel Mechanism

Antonio E. Lacerda, Yuri A. Kuryshev, Yuan Chen et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 93 citations

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