Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss

Yuki Nakao, Takao Fukuda, Qunzhou Zhang, +15

Acta Biomaterialia

Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1

Atsuo T. Sasaki, Takaharu Taketomi, Reiko Kato, +7

Nature Cell Biology

Systems BiologySignal TransductionCell RegulationSignaling PathwayMolecular Regulation +7

Identification of a Dominant Negative Mutant of Sprouty That Potentiates Fibroblast Growth Factor- but Not Epidermal Growth Factor-induced ERK Activation

Atsuo T. Sasaki, Takaharu Taketomi, Toru Wakioka, +2

Journal of Biological Chemistry

Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia

Takaharu Taketomi, Daigo Yoshiga, Koji Taniguchi, +10

Nature Neuroscience

Neuronal HyperplasiaEsophageal AchalasiaEpendymaEsophagusNeuroanatomy +6

Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation

Reiko Kato, Atsushi Nonami, Takaharu Taketomi, +4

Biochemical and Biophysical Research Communications

Signal TransductionCell RegulationSignaling PathwayMammalian Spred-3Molecular Regulation +8

Spred-1 Negatively Regulates Interleukin-3-mediated ERK/Mitogen-activated Protein (MAP) Kinase Activation in Hematopoietic Cells

Atsushi Nonami, Reiko Kato, Koji Taniguchi, +6

Journal of Biological Chemistry

Model analysis of difference between EGF pathway and FGF pathway

Satoshi Yamada, Takaharu Taketomi, Akihiko Yoshimura

Biochemical and Biophysical Research Communications

Fgf PathwaySignal TransductionHuman GrowthMorphogenesisFibroblast Growth Factor +9

DM-20, a proteolipid apoprotein, is an encephalitogen of acute and relapsing autoimmune encephalomyelitis in mice.

Masumi Endoh, Takeshi Tabira, Tatsuhide Kunishita, +3

The Journal of Immunology

ImmunologyProteolipid ApoproteinImmune SystemImmunotherapyNeuroinflammation +17

Extracellular vesicles derived from GMSCs stimulated with TNF-α and IFN-α promote M2 macrophage polarization via enhanced CD73 and CD5L expression

Yukari Watanabe, Takao Fukuda, Chikako Hayashi, +11

Scientific Reports

Mammalian Sprouty4 Suppresses Ras-Independent ERK Activation by Binding to Raf1

Atsuo T. Sasaki, Takaharu Taketomi, Reiko Kato, +7

Cell Cycle

Systems BiologySignal TransductionCell RegulationSignaling PathwayMolecular Regulation +7