Tom Sercu

Evolutionary-scale prediction of atomic-level protein structure with a language model

Zeming Lin, Halil Akin, Roshan Rao et al. · Science · 2023 · 4.2K citations · Full text

Engineering, Machine Learning, Structural Bioinformatics +17

Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences

Alexander Rives, Joshua Meier, Tom Sercu et al. · Proceedings of the National Academy of Sciences · 2021 · 2.8K citations · Full text

Language models enable zero-shot prediction of the effects of mutations on protein function

Joshua Meier, Roshan Rao, Robert Verkuil et al. · 2021 · 635 citations · Full text

Structured Prediction, Engineering, Machine Learning +21

Evolutionary-scale prediction of atomic level protein structure with a language model

Zeming Lin, Halil Akin, Roshan Rao et al. · 2022 · 520 citations · Full text

Engineering, Structural Bioinformatics, Biomolecular Structure Prediction +17

Simulating 500 million years of evolution with a language model

Thomas Hayes, Roshan Rao, Halil Akin et al. · Science · 2025 · 432 citations