Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency.

Marcel Garcia, Danielle Derocq, Pascal Pujol, +1

PubMed

Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decreases the metastatic and invasive potential of the cells.

Danielle Derocq, Gilles Freiss, Henri Rochefort

Proceedings of the National Academy of Sciences

Estrogen ReceptorsBreast OncologyEstrogen Receptor GeneInvasive PotentialMedicine +10

Effects of Plasma Estrogen Sulfates in Mammary Cancer Cells*

Françoise Vignon, M. Terqui, B R Westley, +2

Endocrinology

Estrogen ConjugatesBreast OncologyGynecologyCell CultureFemale Reproductive Function +19

Processing of Human Cathepsin D Is Independent of Its Catalytic Function and Auto-Activation: Involvement of Cathepsins L and B

Valérie Laurent‐Matha, Danielle Derocq, Christine Prébois, +2

The Journal of Biochemistry

Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells

Murielle Glondu, Emmanuelle Liaudet‐Coopman, Danielle Derocq, +3

Oncogene

MedicineImmunologyBreast CancerExperimental Lung MetastasisTumor Suppressor +6

Effect of estradiol on the ultrastructure of the MCF7 human breast cancer cells in culture.

P. Vic, Françoise Vignon, Danielle Derocq, +1

PubMed

Breast OncologyGynecologyCancer BiologyCellular PhysiologyTumor Biology +16

Cloning and Sequencing of the 52K Cathepsin D Complementary Deoxyribonucleic Acid of MCF7 Breast Cancer Cells and Mapping on Chromosome 11

Patrick Augereau, Marcel Garcia, Marie‐Geneviève Mattéi, +6

Molecular Endocrinology

Breast OncologyImmunologyMolecular BiologyCancer BiologyTumor Biology +16

Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies

Yahya Ashraf, Hanane Mansouri, Valérie Laurent‐Matha, +34

Journal for ImmunoTherapy of Cancer

Characterization of monoclonal antibodies to the estrogen-regulated Mr 52,000 glycoprotein and their use in MCF7 cells.

Marcel Garcia, Françoise Capony, Danielle Derocq, +3

PubMed

Immunocytochemical TechniqueImmunologyPathologyImmunophenotypingImmunotherapy +16

Breast cancer cell invasiveness: Correlation with protein kinase C activity and differential regulation by phorbol ester in estrogen receptor-positive and -negative cells

Nadine Platet, Corinne Prévostel, Danielle Derocq, +3

International Journal of Cancer