Processing of Human Cathepsin D Is Independent of Its Catalytic Function and Auto-Activation: Involvement of Cathepsins L and B

Valérie Laurent‐Matha, Danielle Derocq, Christine Prébois, +2

The Journal of Biochemistry

Interactions of Cathepsin-D and Insulin-Like Growth Factor-II (IGF-II) on the IGF-II/Mannose-6-Phosphate Receptor in Human Breast CancerCells and Possible Consequences on Mitogenic Activity of IGF-II

M. Mathieu, Henri Rochefort, Bruno Barenton, +1

Molecular Endocrinology

Proteinlipid InteractionBreast OncologyIgf-ii InteractionMitogenic ActivityCross-linking Experiments +21

Catalytically inactive human cathepsin D triggers fibroblast invasive growth

Valérie Laurent‐Matha, Sharon Maruani-Herrmann, Christine Prébois, +12

The Journal of Cell Biology

BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy

Salwa Sebti, Christine Prébois, Esther Pérez-Gracia, +12

Proceedings of the National Academy of Sciences

Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment

Valérie Laurent‐Matha, Pitter F. Huesgen, Olivier Masson, +12

The FASEB Journal

Cathepsin-D, a Key Protease in Breast Cancer, Is Up-Regulated in Obese Mouse and Human Adipose Tissue, and Controls Adipogenesis

Olivier Masson, Christine Prébois, Danielle Derocq, +7

PLoS ONE

Breast OncologyHuman Adipose TissueKey ProteaseImmunologyPathology +20

Protein-tyrosine Phosphatase PTPL1/FAP-1 Triggers Apoptosis in Human Breast Cancer Cells

Guillaume Bompard, Carole Puech, Christine Prébois, +2

Journal of Biological Chemistry

Signal TransductionSignaling PathwayReceptor Tyrosine KinaseApoptosisCell Death +8

Pro-cathepsin D interacts with the extracellular domain of the β chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth

Mélanie Beaujouin, Christine Prébois, Danielle Derocq, +13

Journal of Cell Science

Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis

Danielle Derocq, Christine Prébois, Mélanie Beaujouin, +4

Oncogene

Cathepsin DProtein FunctionSignal TransductionProtein SecretionBiochemistry +10

BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization

Salwa Sebti, Christine Prébois, Esther Pérez-Gracia, +12

Autophagy