Stefanie A. Kane

HC-030031, a TRPA1 Selective Antagonist, Attenuates Inflammatory- and Neuropathy-Induced Mechanical Hypersensitivity

Samer R. Eid, Eric D. Crown, Eric L. Moore et al. · Molecular Pain · 2008 · 449 citations · Full text

Nursing, Pharmacology, Pharmacotherapy +17

Differential distribution of calcitonin gene-related peptide and its receptor components in the human trigeminal ganglion

Sajedeh Eftekhari, Christopher Salvatore, Amy Calamari et al. · Neuroscience · 2010 · 335 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Receptor Activity-modifying Protein 1 Determines the Species Selectivity of Non-peptide CGRP Receptor Antagonists

John Mallee, Christopher Salvatore, Beatrice LeBourdellès et al. · Journal of Biological Chemistry · 2002 · 191 citations · Full text

Medicine, Molecular Biology, Pharmacology +17

Potent, Orally Bioavailable Calcitonin Gene-Related Peptide Receptor Antagonists for the Treatment of Migraine:  Discovery of <i>N</i> -[(3 <i>R</i> ,6 <i>S</i> )-6-(2,3-Difluorophenyl)-2-oxo-1- (2,2,2-trifluoroethyl)azepan-3-yl]-4- (2-oxo-2,3-dihydro-1 <i>H</i> -imidazo[4,5- <i>b</i> ]pyridin- 1-yl)piperidine-1-carboxamide (MK-0974)

Daniel V. Paone, Anthony W. Shaw, Diem N. Nguyen et al. · Journal of Medicinal Chemistry · 2007 · 146 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Pharmacological Characterization of MK-0974 [N-[(3 R,6 S)-6-(2,3-Difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1 H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide], a Potent and Orally Active Calcitonin Gene-Related Peptide Receptor Antagonist for the Treatment of Migraine

Christopher Salvatore, James C. Hershey, Halea A. Corcoran et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 146 citations

Medicine, Medicinal Chemistry, Pharmacology +14