Concepedia

David J. Kopecky

DJ

Statistics

Publications

15

Citations

2.4K

H-Index

14

Active since

1997

Affiliations

Amgen (United States)(Current)

California Institute of Technology

University of California, Irvine

David J. Kopecky is an author at Amgen (United States) specializing in medicinal chemistry, drug discovery, and potency optimization.

Publications per year

1997–2020

15

Publications

15

Discovery of a Covalent Inhibitor of KRAS<sup>G12C</sup> (AMG 510) for the Treatment of Solid Tumors

Brian A. Lanman, Jennifer R. Allen, John G. Allen et al. · Journal of Medicinal Chemistry · 2019 · 722 citations · Full text

, , +16

Pseudoephedrine as a Practical Chiral Auxiliary for the Synthesis of Highly Enantiomerically Enriched Carboxylic Acids, Alcohols, Aldehydes, and Ketones

Andrew G. Myers, Bryant H. Yang, Hou Chen et al. · Journal of the American Chemical Society · 1997 · 563 citations

, , +9

Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA–Cap Interaction

Xiaoqi Chen, David J. Kopecky, Jeff Mihalic et al. · Journal of Medicinal Chemistry · 2012 · 224 citations · Full text

, , +16

Mukaiyama Aldol−Prins Cyclization Cascade Reaction:  A Formal Total Synthesis of Leucascandrolide A

David J. Kopecky, Scott D. Rychnovsky · Journal of the American Chemical Society · 2001 · 183 citations

, , +8

Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction

Yosup Rew, Daqing Sun, Felix González-López de Turiso et al. · Journal of Medicinal Chemistry · 2012 · 169 citations · Full text

, , +14

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