Annie J. Zalon

Loss of the Spinocerebellar Ataxia type 3 disease protein ATXN3 alters transcription of multiple signal transduction pathways

Li Zeng, Dapeng Zhang, Hayley S. McLoughlin et al. · PLoS ONE · 2018 · 34 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

<scp>Antisense Oligonucleotide</scp> Silencing Reverses Abnormal Neurochemistry in Spinocerebellar Ataxia 3 Mice

Hayley S. McLoughlin, Katherine Gundry, Orion Rainwater et al. · Annals of Neurology · 2023 · 31 citations · Full text

Life Sciences, Neurology, Neuroscience +15

Impaired Autophagic-Lysosomal Fusion in Parkinson's Patient Midbrain Neurons Occurs through Loss of ykt6 and Is Rescued by Farnesyltransferase Inhibition

Caleb Pitcairn, Naomi Murata, Annie J. Zalon et al. · Journal of Neuroscience · 2023 · 27 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Antisense Oligonucleotide Therapy Targeted Against ATXN3 Improves Potassium Channel–Mediated Purkinje Neuron Dysfunction in Spinocerebellar Ataxia Type 3

David D. Bushart, Annie J. Zalon, Hongjiu Zhang et al. · The Cerebellum · 2020 · 26 citations · Full text

Life Sciences, Molecular Genetics, Neuroscience +12

ASOs are an effective treatment for disease-associated oligodendrocyte signatures in premanifest and symptomatic SCA3 mice

Kristen H. Schuster, Annie J. Zalon, Danielle M. DiFranco et al. · Molecular Therapy · 2024 · 19 citations · Full text

Life Sciences, Neurology, Neuroscience +16