Orion Rainwater

Antisense oligonucleotide–mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles

Jillian Friedrich, Holly Kordasiewicz, Brennon O’Callaghan et al. · JCI Insight · 2018 · 130 citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Magnetic Resonance Spectroscopy +15

Brain Derived Neurotrophic Factor (BDNF) Delays Onset of Pathogenesis in Transgenic Mouse Model of Spinocerebellar Ataxia Type 1 (SCA1)

Aaron Mellesmoen, Carrie Sheeler, Austin Ferro et al. · Frontiers in Cellular Neuroscience · 2019 · 50 citations · Full text

Cerebellar contribution to the cognitive alterations in SCA1: evidence from mouse models

Melissa Asher, Juao-Guilherme Rosa, Orion Rainwater et al. · Human Molecular Genetics · 2019 · 30 citations · Full text

<scp>Antisense Oligonucleotide</scp> Silencing Reverses Abnormal Neurochemistry in Spinocerebellar Ataxia 3 Mice

Hayley S. McLoughlin, Katherine Gundry, Orion Rainwater et al. · Annals of Neurology · 2023 · 27 citations · Full text

Assessing recovery from neurodegeneration in spinocerebellar ataxia 1: Comparison of in vivo magnetic resonance spectroscopy with motor testing, gene expression and histology

Gülin Öz, Emily Kittelson, Döne Demirgöz et al. · Neurobiology of Disease · 2014 · 25 citations · Full text

Neurodegenerative Diseases, Motor Testing, Spinocerebellar Ataxia 1 +10