Zihong Chen

Serine Catabolism Feeds NADH when Respiration Is Impaired

Lifeng Yang, Juan Carlos García‐Cañaveras, Zihong Chen et al. · Cell Metabolism · 2020 · 196 citations · Full text

Animal Physiology, Energy Metabolism, Biochemistry +7

Mitochondrial ATP generation is more proteome efficient than glycolysis

Yihui Shen, Hoang V. Dinh, Edward R. Cruz et al. · Nature Chemical Biology · 2024 · 95 citations · Full text

Mitochondrial Function, Biochemistry, Mitochondrial Atp Generation +3

Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition

Hongyu Ding, Zihong Chen, Katherine Wu et al. · Science Advances · 2021 · 81 citations · Full text

Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras–Driven Tumor Growth or Metastasis

Jonathan M. Ghergurovich, Mark Esposito, Zihong Chen et al. · Cancer Research · 2020 · 44 citations · Full text

Cell Proliferation, Metabolic Remodeling, Cancer Biology +19

One-carbon unit supplementation fuels purine synthesis in tumor-infiltrating T cells and augments checkpoint blockade

Xincheng Xu, Zihong Chen, Caroline Bartman et al. · Cell chemical biology · 2024 · 19 citations · Full text

Augments Checkpoint Blockade, Cancer Immunosurveillance, Oncology +11