Lyal E. Tressler

Three‐Dimensional Database Mining Identifies a Unique Chemotype that Unites Structurally Diverse Botulinum Neurotoxin Serotype A Inhibitors in a Three‐Zone Pharmacophore

Ann Hermone, James C. Burnett, Jonathan E. Nuss et al. · ChemMedChem · 2008 · 35 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Multi-Faceted Proteomic Characterization of Host Protein Complement of Rift Valley Fever Virus Virions and Identification of Specific Heat Shock Proteins, Including HSP90, as Important Viral Host Factors

Jonathan E. Nuss, Kylene Kehn‐Hall, Ashwini Benedict et al. · PLoS ONE · 2014 · 30 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Development of Cell-Based Assays to Measure Botulinum Neurotoxin Serotype A Activity Using Cleavage-Sensitive Antibodies

Jonathan E. Nuss, Gordon Ruthel, Lyal E. Tressler et al. · SLAS DISCOVERY · 2009 · 28 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Post-Intoxication Inhibition of Botulinum Neurotoxin Serotype A within Neurons by Small-Molecule, Non-Peptidic Inhibitors

Gordon Ruthel, James C. Burnett, Jonathan E. Nuss et al. · Toxins · 2011 · 27 citations · Full text

Medicine, Neurobiology, Neuroscience +14

The Osmolyte Trimethylamine N-Oxide (TMAO) Increases the Proteolytic Activity of Botulinum Neurotoxin Light Chains A, B, and E: Implications for Enhancing Analytical Assay Sensitivity

Jonathan E. Nuss, Laura M. Wanner, Lyal E. Tressler et al. · SLAS DISCOVERY · 2010 · 12 citations · Full text

Life Sciences, Biochemistry, Microbiology +16