Stuart J. Conway

Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate

Rui Chen, Ignacio Leyva-Valencia, Fei Zhong et al. · The Journal of Cell Biology · 2004 · 398 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

2-Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1,4,5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels

Claire M. Peppiatt‐Wildman, Tony Collins, Lauren J MacKenzie et al. · Cell Calcium · 2003 · 291 citations · Full text

Medicine, Biochemistry, Pharmacology +15

Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

Duncan A. Hay, Oleg Fedorov, Sarah Martin et al. · Journal of the American Chemical Society · 2014 · 285 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

3,5-Dimethylisoxazoles Act As Acetyl-lysine-mimetic Bromodomain Ligands

David S. Hewings, Minghua Wang, Martin Philpott et al. · Journal of Medicinal Chemistry · 2011 · 223 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

The use of phosphate bioisosteres in medicinal chemistry and chemical biology

Thomas Elliott, Aine Slowey, Yulin Ye et al. · MedChemComm · 2012 · 184 citations

Pharmacy, Chemical Biology, Medicinal Chemistry +11