V. Sashi Gopaul

Overcoming the Genotoxicity of a Pyrrolidine Substituted Arylindenopyrimidine As a Potent Dual Adenosine A_2A/A₁Antagonist by Minimizing Bioactivation to an Iminium Ion Reactive Intermediate

Heng‐Keang Lim, Jie Chen, Carlo Sensenhauser et al. · Chemical Research in Toxicology · 2011 · 34 citations

Pharmacy, Pharmacology, Toxicology +17

Amino Acid Conjugates: Metabolites of 2-Propylpentanoic Acid (Valproic Acid) in Epileptic Patients

V. Sashi Gopaul, Wei Tang, K Farrell et al. · Drug Metabolism and Disposition · 2003 · 21 citations

Medicine, Pharmacokinetics, Pharmacology +17

Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, following Administration of an Oral Radiolabeled Microtracer Dose in Humans

Chandrali Bhattacharya, Ann-Sofie Sandinge, Ryan A. Bragg et al. · Drug Metabolism and Disposition · 2023 · 12 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Biotransformation of the Novel Myeloperoxidase Inhibitor AZD4831 in Preclinical Species and Humans

Ulrik Jurva, Lars Weidolf, Ann-Sofie Sandinge et al. · Drug Metabolism and Disposition · 2023 · 11 citations · Full text

Life Sciences, Pharmacokinetics, Pharmacology +17

Effects of mineral oil administration on the pharmacokinetics, metabolism and pharmacodynamics of atorvastatin and pravastatin in mice and dogs

V. Sashi Gopaul, Elsbet Pieterman, P. Hans et al. · European Journal of Pharmaceutical Sciences · 2021 · 10 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +9