Daniel Merk

Neurogenesis from Sox2 expressing cells in the adult cerebellar cortex

Julia Ahlfeld, Severin Filser, Felix Schmidt et al. · Scientific Reports · 2017 · 52 citations · Full text

A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors

Julia E. Neumann, Annika K. Wefers, Sander Lambo et al. · Nature Medicine · 2017 · 52 citations

Tumoral Pathology, Developmental Biology, Tissue Development +8

Preferential sensitivity to HDAC inhibitors in tumors with CREBBP mutation

Malte Hellwig, Daniel Merk, Beat Lutz et al. · Cancer Gene Therapy · 2019 · 48 citations

Tumor Biology, Hdac Inhibitors, Oncogenic Agent +8

Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma

Daniel Merk, Jasmin Ohli, Natalie D. Merk et al. · Developmental Cell · 2018 · 45 citations · Full text

Rubinstein-taybi Syndrome, Mendelian Disorder, Genetic Disorder +7

A large-scale drug screen identifies selective inhibitors of class I HDACs as a potential therapeutic option for SHH medulloblastoma

Ekaterina Pak, Ethan L. MacKenzie, Xuesong Zhao et al. · Neuro-Oncology · 2019 · 37 citations · Full text