Brad G. Hoffman

The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes

Tess Tsai-Hsiu Lu, Steffen Heyne, Erez Dror et al. · Cell Metabolism · 2018 · 146 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

A mouse atlas of gene expression: Large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells

Asim Siddiqui, Jaswinder Khattra, Allen Delaney et al. · Proceedings of the National Academy of Sciences · 2005 · 119 citations · Full text

Life Sciences, Developmental Biology, Genetics +10

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver

Brad G. Hoffman, Gordon Robertson, Bogard Zavaglia et al. · Genome Research · 2010 · 118 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Identification and analysis of murine pancreatic islet enhancers

Bryan Tennant, A. Gordon Robertson, Marabeth M. Kramer et al. · Diabetologia · 2012 · 65 citations · Full text

Medicine, Molecular Biology, Molecular Genetics +11

Paracrine signalling loops in adult human and mouse pancreatic islets: netrins modulate beta cell apoptosis signalling via dependence receptors

Yu Hsuan Carol Yang, Marta Szabat, C. Bragagnini et al. · Diabetologia · 2011 · 63 citations · Full text

Life Sciences, Cell Biology, Endocrinology +16