Differential requirement for the activation of the inflammasome for processing and release of IL-1β in monocytes and macrophages

Mihai G. Netea, Claudia A. Nold‐Petry, Marcel F. Nold, +13

Blood

siRNA injection induces sequence-independent protection in Penaeus monodon against white spot syndrome virus

Marcel Westenberg, Bas Heinhuis, D. Zuidema, +1

Virus Research

Molecular VirologyPathogenesisViral PathogenesisPathologyVirology +5

Inflammation-dependent secretion and splicing of IL-32γ in rheumatoid arthritis

Bas Heinhuis, Marije I. Koenders, F.A. van de Loo, +3

Proceedings of the National Academy of Sciences

Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages

Rob J.W. Arts, Theo S. Plantinga, Sander Tuit, +10

OncoImmunology

InflammationCytokineTumor-associated MacrophagesAerobic GlycolysisMetabolic Reprogramming +13

STAT1 Hyperphosphorylation and Defective IL12R/IL23R Signaling Underlie Defective Immunity in Autosomal Dominant Chronic Mucocutaneous Candidiasis

Sanne P. Smeekens, Theo S. Plantinga, Frank L. van de Veerdonk, +10

PLoS ONE

InflammationCytokineStat1 Arg274trp MutationsAllergyAutoimmune Disease +13

Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade

Bas Heinhuis, Marije I. Koenders, Piet L. van Riel, +5

Annals of the Rheumatic Diseases

IL-32 Promotes Angiogenesis

Claudia A. Nold‐Petry, Ina Rudloff, Yvonne Baumer, +17

The Journal of Immunology

ImmunologyImmune RegulationCell DeathPathologyImmunotherapeutics +19

Interleukin 32 (IL-32) Contains a Typical α-Helix Bundle Structure That Resembles Focal Adhesion Targeting Region of Focal Adhesion Kinase-1

Bas Heinhuis, Marije I. Koenders, Wim B. van den Berg, +3

Journal of Biological Chemistry

Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects

Cajsa Davegårdh, Christa Broholm, Alexander Perfilyev, +16

BMC Medicine

Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis

Leo A. B. Joosten, Bas Heinhuis, Shahla Abdollahi‐Roodsaz, +10

Proceedings of the National Academy of Sciences

ImmunologyMolecular BiologyNod2 DeficiencyNod1 MutationInflammation +14