Rob J.W. Arts

mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

Shih‐Chin Cheng, Jessica Quintin, Robert A. Cramer et al. · Science · 2014 · 2.1K citations · Full text

Microbial Pathogens, Trained Immunity, Innate Immune System +25

BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity

Rob J.W. Arts, Simone J.C.F.M. Moorlag, Boris Novakovic et al. · Cell Host & Microbe · 2018 · 1.1K citations · Full text

Vaccination, Vaccine Development, Experimental Viral Infection +8

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity

Rob J.W. Arts, Boris Novakovic, Rob ter Horst et al. · Cell Metabolism · 2016 · 807 citations · Full text

Autoimmune Disease, Allergy, Trained Immunity +9

Metabolic Induction of Trained Immunity through the Mevalonate Pathway

Siroon Bekkering, Rob J.W. Arts, Boris Novakovic et al. · Cell · 2018 · 707 citations · Full text

Trained Immunity, Physiology, Immunology +5

β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance

Boris Novakovic, Ehsan Habibi, Shuang-Yin Wang et al. · Cell · 2016 · 653 citations · Full text