Valérie Clerin

LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse

Elaine Quinet, Michael Basso, Anita Halpern et al. · Journal of Lipid Research · 2009 · 104 citations · Full text

2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[<i>H</i>]quinoline-4-carboxylic Acid (PSI-697):  Identification of a Clinical Candidate from the Quinoline Salicylic Acid Series of P-Selectin Antagonists

Neelu Kaila, Kristin Janz, Adrian Huang et al. · Journal of Medicinal Chemistry · 2006 · 82 citations · Full text

Immunology, Clinical Candidate, Pharmacotherapy +21

Indazole-Based Liver X Receptor (LXR) Modulators with Maintained Atherosclerotic Lesion Reduction Activity but Diminished Stimulation of Hepatic Triglyceride Synthesis

Jay Wrobel, Robert J. Steffan, Susan Bowen et al. · Journal of Medicinal Chemistry · 2008 · 74 citations · Full text

A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia

Lacramioara Ivanciu, Raffaella Toso, Paris Margaritis et al. · Nature Biotechnology · 2011 · 71 citations

Hematology, Immunology, Pathology +5

Phosphodiesterase Type 5 Inhibition Reduces Albuminuria in Subjects with Overt Diabetic Nephropathy

Wim H. Scheele, Susan M. Diamond, Jeremy D. Gale et al. · Journal of the American Society of Nephrology · 2016 · 64 citations · Full text