Concepedia

Jay Wrobel

JW

Statistics

Publications

64

Citations

3.5K

H-Index

37

Active since

1980

Affiliations

Women's Health Research Institute(Current)

Karo Pharma (Sweden)

Fox Chase Chemical Diversity Center

South College

University of Pennsylvania

Jay Wrobel is an author at Women's Health Research Institute specializing in pharmacology, medicinal chemistry, and drug discovery.

ORCID

Publications per year

1980–2021

64

Publications

64

Mechanism and synthetic utility of boron trifluoride etherate-promoted organolithium additions

Michael J. Eis, Jay Wrobel, Bruce Ganem · Journal of the American Chemical Society · 1984 · 230 citations

, , +9

Design, Synthesis, and SAR of New Pyrrole-Oxindole Progesterone Receptor Modulators Leading to 5-(7-Fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1<i>H</i>-indol-5-yl)-1-methyl-1<i>H</i>-pyrrole-2-carbonitrile (WAY-255348)

Andrew Fensome, William R. Adams, Andrea L. Adams et al. · Journal of Medicinal Chemistry · 2008 · 198 citations · Full text

, , +17

Novel spirosuccinimides with incorporated isoindolone and benzisothiazole 1,1-dioxide moieties as aldose reductase inhibitors and antihyperglycemic agents

Jay Wrobel, Arlene Dietrich, S. Woolson et al. · Journal of Medicinal Chemistry · 1992 · 191 citations

, , +6

Discovery of XL335 (WAY-362450), a Highly Potent, Selective, and Orally Active Agonist of the Farnesoid X Receptor (FXR)

Brenton Flatt, Richard Martin, Tielin Wang et al. · Journal of Medicinal Chemistry · 2009 · 161 citations · Full text

, , +17

PTP1B Inhibition and Antihyperglycemic Activity in the ob/ob Mouse Model of Novel 11-Arylbenzo[<i>b</i>]naphtho[2,3-<i>d</i>]furans and 11-Arylbenzo[<i>b</i>]naphtho[2,3-<i>d</i>]thiophenes

Jay Wrobel, Janet Sredy, Christopher Moxham et al. · Journal of Medicinal Chemistry · 1999 · 126 citations · Full text

, , +6

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