Jessica Orf

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

Lei Zhang, Ziyi Li, Katarzyna M. Skrzypczynska et al. · Cell · 2020 · 1.6K citations · Full text

Medicine, Cell Biology, Oncology +16

Cabozantinib (XL184), a Novel MET and VEGFR2 Inhibitor, Simultaneously Suppresses Metastasis, Angiogenesis, and Tumor Growth

F. Michael Yakes, Jason Chen, Jenny Tan et al. · Molecular Cancer Therapeutics · 2011 · 1.3K citations · Full text

Medicine, Oncology, Pharmacology +17

Metastatic properties and genomic amplification of the tyrosine kinase gene <i>ACK1</i>

Edward H. van der Horst, Yan Degenhardt, Astrid Strelow et al. · Proceedings of the National Academy of Sciences · 2005 · 145 citations · Full text

Medicine, Cancer Biology, Oncology +17

Activity of tumor-associated macrophage depletion by CSF1R blockade is highly dependent on the tumor model and timing of treatment

Sarah A. O’Brien, Jessica Orf, Katarzyna M. Skrzypczynska et al. · Cancer Immunology Immunotherapy · 2021 · 60 citations · Full text

Medicine, Immunology, Oncology +17

Preclinical Evaluation of AMG 925, a FLT3/CDK4 Dual Kinase Inhibitor for Treating Acute Myeloid Leukemia

Kathleen S. Keegan, Cong Li, Zhihong Li et al. · Molecular Cancer Therapeutics · 2014 · 35 citations · Full text

Medicine, Oncology, Pharmacology +17