Olivier Van der Poorten

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists

Tobias Claff, Jing Yu, Véronique Blais et al. · Science Advances · 2019 · 126 citations · Full text

Medicine, Chemistry, Pharmacology +16

Synthesis and biological evaluation of compact, conformationally constrained bifunctional opioid agonist – Neurokinin-1 antagonist peptidomimetics

Karel Guillemyn, Patrycja Kleczkowska, Anna Leśniak et al. · European Journal of Medicinal Chemistry · 2014 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structure-Based Design of Melanocortin 4 Receptor Ligands Based on the SHU-9119-hMC4R Cocrystal Structure

Charlotte Martin, Luis E. Gimenez, Savannah Y. Williams et al. · Journal of Medicinal Chemistry · 2020 · 16 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

T3P-Promoted, Mild, One-Pot Syntheses of Constrained Polycyclic Lactam Dipeptide Analogues via Stereoselective Pictet–Spengler and Meyers Lactamization Reactions

Mouhamad Jida, Olivier Van der Poorten, Karel Guillemyn et al. · Organic Letters · 2015 · 14 citations

Pharmacy, Chemistry, Medicinal Chemistry +10

Azepinone-Containing Tetrapeptide Analogues of Melanotropin Lead to Selective <i>h</i>MC4R Agonists and <i>h</i>MC5R Antagonist

Olivier Van der Poorten, Krisztina Fehér, Koen Buysse et al. · ACS Medicinal Chemistry Letters · 2014 · 13 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15