Karel Guillemyn

Structural basis for bifunctional peptide recognition at human δ-opioid receptor

Gustavo Fenalti, Nadia A. Zatsepin, Cecilia Betti et al. · Nature Structural & Molecular Biology · 2015 · 175 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +6

Bifunctional Peptide-Based Opioid Agonist–Nociceptin Antagonist Ligands for Dual Treatment of Acute and Neuropathic Pain

Karel Guillemyn, Joanna Starnowska-Sokół, Camille Lagard et al. · Journal of Medicinal Chemistry · 2016 · 48 citations · Full text

Nanobody‐Enabled Reverse Pharmacology on G‐Protein‐Coupled Receptors

Els Pardon, Cecilia Betti, Toon Laeremans et al. · Angewandte Chemie International Edition · 2018 · 45 citations

A bifunctional-biased mu-opioid agonist–neuropeptide FF receptor antagonist as analgesic with improved acute and chronic side effects

Armand Drieu la Rochelle, Karel Guillemyn, Maria Dumitrascuta et al. · Pain · 2018 · 42 citations

Structure Revision of <i>N</i>-Mercapto-4-formylcarbostyril Produced by <i>Pseudomonas fluorescens</i> G308 to 2-(2-Hydroxyphenyl)thiazole-4-carbaldehyde [aeruginaldehyde]

Lumeng Ye, Pierre Cornélis, Karel Guillemyn et al. · Natural Product Communications · 2014 · 33 citations

Medicinal Chemistry, Biosynthesis, Bioorganic Chemistry +14